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Open Access
Peer-reviewed
Research Article
A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination
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Timothy Wessler ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
¶‡ These authors share first authorship on this work.
Affiliations Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
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Louis R. Joslyn ,
Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
¶‡ These authors share first authorship on this work.
Affiliations Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
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H. Jacob Borish,
Roles Data curation, Methodology, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Hannah P. Gideon,
Roles Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing
Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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JoAnne L. Flynn,
Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing
Affiliation Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America
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Denise E. Kirschner ,
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: kirschne@umich.edu (DEK); linderma@umich.edu (JJL)
Affiliation Department of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, United States of America
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Jennifer J. Linderman
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing
* E-mail: kirschne@umich.edu (DEK); linderma@umich.edu (JJL)
Affiliation Department of Chemical Engineering, University of Michigan, Ann Arbor, Michigan, United States of America
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A computational model tracks whole-lung Mycobacterium tuberculosis infection and predicts factors that inhibit dissemination
- Timothy Wessler,
- Louis R. Joslyn,
- H. Jacob Borish,
- Hannah P. Gideon,
- JoAnne L. Flynn,
- Denise E. Kirschner,
- Jennifer J. Linderman
![PLOS](/resource/img/logo-plos.png)
- Published: May 20, 2020
- https://doi.org/10.1371/journal.pcbi.1007280