Benchmarking network propagation methods for disease gene identification

Sergio Picart-Armada; Steven J. Barrett; David R. Willé; Alexandre Perera-Lluna; Alex Gutteridge; Benoit H. Dessailly

doi:10.1371/journal.pcbi.1007276

Loading metrics

Open Access

Peer-reviewed

Research Article

Benchmarking network propagation methods for disease gene identification

Sergio Picart-Armada ,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

* E-mail: sergi.picart@upc.edu

Affiliations B2SLab, Departament d’Enginyeria de Sistemes, Automàtica i Informàtica Industrial, Universitat Politècnica de Catalunya, CIBER-BBN, Barcelona, Spain, Networking Biomedical Research Centre in the subject area of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain, Institut de Recerca Pediàtrica Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain

http://orcid.org/0000-0002-6426-8204

⨯
Steven J. Barrett,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Research Statistics, GSK, Stevenage, United Kingdom

http://orcid.org/0000-0002-3570-3131

⨯
David R. Willé,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Research Statistics, GSK, Stevenage, United Kingdom
⨯
Alexandre Perera-Lluna,

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

Affiliations B2SLab, Departament d’Enginyeria de Sistemes, Automàtica i Informàtica Industrial, Universitat Politècnica de Catalunya, CIBER-BBN, Barcelona, Spain, Networking Biomedical Research Centre in the subject area of Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Madrid, Spain, Institut de Recerca Pediàtrica Hospital Sant Joan de Déu, Esplugues de Llobregat, Spain
⨯
Alex Gutteridge,

Roles Conceptualization, Supervision, Validation, Writing – review & editing

Affiliation Computational Biology and Statistics, GSK, Stevenage, United Kingdom

http://orcid.org/0000-0001-7515-634X

⨯
Benoit H. Dessailly

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation GSK Vaccines, Rixensart, Belgium
⨯

Benchmarking network propagation methods for disease gene identification

Sergio Picart-Armada,
Steven J. Barrett,
David R. Willé,
Alexandre Perera-Lluna,
Alex Gutteridge,
Benoit H. Dessailly

Published: September 3, 2019
https://doi.org/10.1371/journal.pcbi.1007276
See the preprint

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Drug discovery
Is the Subject Area "Drug discovery" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.
Genetics of disease
Is the Subject Area "Genetics of disease" applicable to this article?

Thanks for your feedback.
Machine learning
Is the Subject Area "Machine learning" applicable to this article?

Thanks for your feedback.
Gene prediction
Is the Subject Area "Gene prediction" applicable to this article?

Thanks for your feedback.
Drug interactions
Is the Subject Area "Drug interactions" applicable to this article?

Thanks for your feedback.
Machine learning algorithms
Is the Subject Area "Machine learning algorithms" applicable to this article?

Thanks for your feedback.
Support vector machines
Is the Subject Area "Support vector machines" applicable to this article?

Thanks for your feedback.