Designing combination therapies with modeling chaperoned machine learning

Yin Zhang; Julie M. Huynh; Guan-Sheng Liu; Richard Ballweg; Kayenat S. Aryeh; Andrew L. Paek; Tongli Zhang

doi:10.1371/journal.pcbi.1007158

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Open Access

Peer-reviewed

Research Article

Designing combination therapies with modeling chaperoned machine learning

Yin Zhang ,

Contributed equally to this work with: Yin Zhang, Julie M. Huynh, Guan-Sheng Liu

Roles Data curation, Methodology

Affiliation Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio, United States of America

http://orcid.org/0000-0002-6127-7535

⨯
Julie M. Huynh ,

Contributed equally to this work with: Yin Zhang, Julie M. Huynh, Guan-Sheng Liu

Roles Data curation

Affiliation Molecular and Cellular Biology, University of Arizona, Tucson, United States of America
⨯
Guan-Sheng Liu ,

Contributed equally to this work with: Yin Zhang, Julie M. Huynh, Guan-Sheng Liu

Roles Writing – review & editing

Affiliation Department of Pharmacology and Systems Physiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America
⨯
Richard Ballweg,

Roles Writing – original draft

Affiliation Department of Pharmacology and Systems Physiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America
⨯
Kayenat S. Aryeh,

Affiliation Molecular and Cellular Biology, University of Arizona, Tucson, United States of America
⨯
Andrew L. Paek ,

Roles Data curation, Formal analysis, Supervision, Writing – review & editing

* E-mail: apaek@email.arizona.edu (ALP); zhangtl@ucmail.uc.edu (TZ)

Affiliation Molecular and Cellular Biology, University of Arizona, Tucson, United States of America

http://orcid.org/0000-0002-2835-8544

⨯
Tongli Zhang

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: apaek@email.arizona.edu (ALP); zhangtl@ucmail.uc.edu (TZ)

Affiliation Department of Pharmacology and Systems Physiology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, United States of America

http://orcid.org/0000-0003-1773-6279

⨯

Designing combination therapies with modeling chaperoned machine learning

Yin Zhang,
Julie M. Huynh,
Guan-Sheng Liu,
Richard Ballweg,
Kayenat S. Aryeh,
Andrew L. Paek,
Tongli Zhang

Published: September 9, 2019
https://doi.org/10.1371/journal.pcbi.1007158

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