Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

• Laurens F. M. Verscheijden,

  Roles Conceptualization, Data curation, Formal analysis, Validation, Visualization, Writing – original draft

  Affiliation Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands

  http://orcid.org/0000-0003-0303-898X

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• Jan B. Koenderink,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands

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• Saskia N. de Wildt,

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands, Intensive Care and Department of Pediatric Surgery, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands

  http://orcid.org/0000-0002-0502-0647

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• Frans G. M. Russel

  Roles Conceptualization, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Frans.Russel@radboudumc.nl

  Affiliation Department of Pharmacology and Toxicology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands

  http://orcid.org/0000-0002-7959-2314

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