Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance

• Yapeng Su,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Institute for Systems Biology, Seattle, Washington, United State of America, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United State of America

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• Marcus Bintz,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular and Medical Pharmacology, University of California – Los Angeles, Los Angeles, California, United State of America

  http://orcid.org/0000-0002-4548-3953

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• Yezi Yang,

  Roles Investigation

  Affiliation Department of Molecular and Medical Pharmacology, University of California – Los Angeles, Los Angeles, California, United State of America

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• Lidia Robert,

  Roles Resources

  Affiliation Department of Medicine, University of California – Los Angeles, Los Angeles, California, United State of America

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• Alphonsus H. C. Ng,

  Roles Investigation

  Affiliations Institute for Systems Biology, Seattle, Washington, United State of America, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United State of America

  http://orcid.org/0000-0003-0074-4598

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• Victoria Liu,

  Roles Investigation

  Affiliation Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United State of America

  http://orcid.org/0000-0003-1845-2497

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• Antoni Ribas,

  Roles Funding acquisition, Investigation, Resources

  Affiliations Department of Molecular and Medical Pharmacology, University of California – Los Angeles, Los Angeles, California, United State of America, Department of Medicine, University of California – Los Angeles, Los Angeles, California, United State of America, Department of Surgery, Division of Surgical-Oncology, University of California – Los Angeles, Los Angeles, California, United State of America, Jonsson Comprehensive Cancer Center, University of California – Los Angeles, Los Angeles, California, United State of America

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• James R. Heath ,

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jheath@systemsbiology.org (J.R.H.); wwei@systemsbiology.org (W.W.)

  Affiliations Institute for Systems Biology, Seattle, Washington, United State of America, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, United State of America, Jonsson Comprehensive Cancer Center, University of California – Los Angeles, Los Angeles, California, United State of America

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• Wei Wei

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jheath@systemsbiology.org (J.R.H.); wwei@systemsbiology.org (W.W.)

  Affiliations Institute for Systems Biology, Seattle, Washington, United State of America, Department of Molecular and Medical Pharmacology, University of California – Los Angeles, Los Angeles, California, United State of America, Jonsson Comprehensive Cancer Center, University of California – Los Angeles, Los Angeles, California, United State of America

  http://orcid.org/0000-0002-1018-7708

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