CancerInSilico: An R/Bioconductor package for combining mathematical and statistical modeling to simulate time course bulk and single cell gene expression data in cancer

• Thomas D. Sherman ,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tsherma4@jhu.edu (TDS); ejfertig@jhmi.edu (EJF)

  Affiliation Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America

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• Luciane T. Kagohara,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America

  http://orcid.org/0000-0003-1706-0950

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• Raymon Cao,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America

  http://orcid.org/0000-0001-8549-8378

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• Raymond Cheng,

  Roles Data curation, Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Science, Math and Computer Science Magnet Program, Poolesville High School, Poolesville, MD United States of America

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• Matthew Satriano,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Department of Mathematics, University of Waterloo, Waterloo, Ontario, Canada

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• Michael Considine,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America

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• Gabriel Krigsfeld,

  Roles Formal analysis, Software, Writing – review & editing

  Affiliation Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America

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• Ruchira Ranaweera,

  Roles Data curation, Validation, Writing – review & editing

  Affiliation Moffitt Cancer Center, Tampa, FL, United States of America

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• Yong Tang,

  Roles Formal analysis, Software, Writing – review & editing

  Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC United States of America

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• Sandra A. Jablonski,

  Roles Data curation, Formal analysis, Validation, Writing – review & editing

  Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC United States of America

  http://orcid.org/0000-0001-7220-8159

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• Genevieve Stein-O'Brien,

  Roles Formal analysis, Software, Validation, Writing – review & editing

  Affiliations Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America, Institute of Genetic Medicine, Johns Hopkins University, Baltimore, MD United States of America

  http://orcid.org/0000-0001-8681-9110

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• Daria A. Gaykalova,

  Roles Formal analysis, Writing – review & editing

  Affiliation Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, MD United States of America

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• Louis M. Weiner,

  Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC United States of America

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• Christine H. Chung,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Moffitt Cancer Center, Tampa, FL, United States of America

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• Elana J. Fertig

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: tsherma4@jhu.edu (TDS); ejfertig@jhmi.edu (EJF)

  Affiliations Department of Oncology, Division of Biostatistics and Bioinformatics, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD United States of America, Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD United States of America, Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD United States of America

  http://orcid.org/0000-0003-3204-342X

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