A complete statistical model for calibration of RNA-seq counts using external spike-ins and maximum likelihood theory

• Rodoniki Athanasiadou ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rodoniki.athanasiadou@nyulangone.org (RA); dan.tranchina@nyu.edu (DT)

  Current address: New York University Langone Health, New York, New York, United States of America

  Affiliation Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, United States of America

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• Benjamin Neymotin,

  Roles Investigation, Writing – review & editing

  Current address: Albert Einstein College of Medicine, Bronx, New York, United States of America

  Affiliation Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, United States of America

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• Nathan Brandt,

  Roles Investigation

  Affiliation Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, United States of America

  http://orcid.org/0000-0002-7774-7749

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• Wei Wang,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Developmental Genetics, Department of Biology, New York University, New York, New York, United States of America

  http://orcid.org/0000-0002-0480-671X

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• Lionel Christiaen,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Center for Developmental Genetics, Department of Biology, New York University, New York, New York, United States of America

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• David Gresham,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, United States of America

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• Daniel Tranchina

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rodoniki.athanasiadou@nyulangone.org (RA); dan.tranchina@nyu.edu (DT)

  Affiliations Department of Biology, New York University, New York, New York, United States of America, Courant Institute of Mathematical Sciences, New York University, New York, New York, United States of America

  http://orcid.org/0000-0002-0439-8349

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