A component overlapping attribute clustering (COAC) algorithm for single-cell RNA sequencing data analysis and potential pathobiological implications

• He Peng,

  Roles Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

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• Xiangxiang Zeng ,

  Roles Investigation, Methodology, Supervision, Visualization

  * E-mail: xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

  Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

  http://orcid.org/0000-0003-1081-7658

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• Yadi Zhou,

  Roles Formal analysis, Investigation, Visualization

  Affiliation Department of Chemistry and Biochemistry, Ohio University, Athens, OH, United States of America

  http://orcid.org/0000-0002-6049-0545

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• Defu Zhang,

  Roles Formal analysis

  Affiliation Department of Computer Science, Xiamen University, Xiamen, Fujian, China

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• Ruth Nussinov ,

  Roles Validation, Writing – review & editing

  * E-mail: xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

  Affiliations Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, National Cancer Institute at Frederick, Frederick, MD, United States of America, Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

  http://orcid.org/0000-0002-8115-6415

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• Feixiong Cheng

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: xzeng@xmu.edu.cn (XZ); nussinor@mail.nih.gov (RN); chengf@ccf.org (FC)

  Affiliations Genomic Medicine Institute, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America, Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, United States of America, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America

  http://orcid.org/0000-0002-1736-2847

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