Predicting protein targets for drug-like compounds using transcriptomics

• Nicolas A. Pabon ,

  Contributed equally to this work with: Nicolas A. Pabon, Yan Xia

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0002-2591-4349

  ⨯
• Yan Xia ,

  Contributed equally to this work with: Nicolas A. Pabon, Yan Xia

  Roles Data curation, Formal analysis, Software, Validation

  Affiliation Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Samuel K. Estabrooks,

  Roles Validation

  Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Zhaofeng Ye,

  Roles Validation

  Affiliation School of Medicine, Tsinghua University, Beijing, China

  ⨯
• Amanda K. Herbrand,

  Roles Validation

  Affiliation Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany

  ⨯
• Evelyn Süß,

  Roles Validation

  Affiliation Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany

  ⨯
• Ricardo M. Biondi,

  Roles Validation

  Affiliation Department of Internal Medicine I, Universitätsklinikum Frankfurt, Frankfurt, Germany

  http://orcid.org/0000-0002-8873-7167

  ⨯
• Victoria A. Assimon,

  Roles Validation

  Affiliation Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America

  ⨯
• Jason E. Gestwicki,

  Roles Validation

  Affiliation Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, California, United States of America

  ⨯
• Jeffrey L. Brodsky,

  Roles Validation

  Affiliation Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  ⨯
• Carlos J. Camacho ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ccamacho@pitt.edu (CJC); zivbj@cs.cmu.edu (ZBJ)

  Affiliation Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0003-1741-8529

  ⨯
• Ziv Bar-Joseph

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: ccamacho@pitt.edu (CJC); zivbj@cs.cmu.edu (ZBJ)

  Affiliation Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

  http://orcid.org/0000-0003-3430-6051

  ⨯