Modeling and prediction of clinical symptom trajectories in Alzheimer’s disease using longitudinal data

• Nikhil Bhagwat ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nikhil153@gmail.com (NB); mallar@cobralab.ca (MMC)

  Affiliations Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, Computational Brain Anatomy Laboratory, Brain Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, Canada, Kimel Family Translational Imaging-Genetics Research Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

  http://orcid.org/0000-0001-6073-7141

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• Joseph D. Viviano,

  Roles Methodology, Validation

  Affiliation Kimel Family Translational Imaging-Genetics Research Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

  http://orcid.org/0000-0001-7016-5212

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• Aristotle N. Voineskos,

  Roles Resources, Supervision

  Affiliations Kimel Family Translational Imaging-Genetics Research Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada, Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada

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• M. Mallar Chakravarty ,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: nikhil153@gmail.com (NB); mallar@cobralab.ca (MMC)

  Affiliations Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada, Computational Brain Anatomy Laboratory, Brain Imaging Center, Douglas Mental Health University Institute, Verdun, Quebec, Canada, Department of Biological and Biomedical Engineering, McGill University, Montreal, Quebec, Canada

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• Alzheimer’s Disease Neuroimaging Initiative