Exploiting glycan topography for computational design of Env glycoprotein antigenicity

• Wen-Han Yu ,

  Contributed equally to this work with: Wen-Han Yu, Peng Zhao, Monia Draghi

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft

  Affiliations Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States of America

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• Peng Zhao ,

  Contributed equally to this work with: Wen-Han Yu, Peng Zhao, Monia Draghi

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliation Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, Georgia, United States of America

  http://orcid.org/0000-0002-9296-5293

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• Monia Draghi ,

  Contributed equally to this work with: Wen-Han Yu, Peng Zhao, Monia Draghi

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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• Claudia Arevalo,

  Roles Investigation, Writing – original draft

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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• Christina B. Karsten,

  Roles Investigation

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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• Todd J. Suscovich,

  Roles Conceptualization, Project administration, Writing – review & editing

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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• Bronwyn Gunn,

  Roles Writing – review & editing

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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• Hendrik Streeck,

  Roles Supervision, Writing – review & editing

  Affiliation Institute for HIV Research, University Hospital Essen, University Duisburg-Essen, Essen, Germany

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• Abraham L. Brass,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Michael Tiemeyer,

  Roles Supervision, Writing – review & editing

  Affiliation Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, Georgia, United States of America

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• Michael Seaman,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

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• John R. Mascola,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States of America

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• Lance Wells ,

  Roles Conceptualization, Data curation, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: galter@mgh.harvard.edu (GA); lauffen@mit.edu (DAL); lwells@ccrc.uga.edu (LW)

  Affiliation Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, The University of Georgia, Athens, Georgia, United States of America

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• Douglas A. Lauffenburger ,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  * E-mail: galter@mgh.harvard.edu (GA); lauffen@mit.edu (DAL); lwells@ccrc.uga.edu (LW)

  Affiliations Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States of America

  http://orcid.org/0000-0002-0050-989X

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• Galit Alter

  Roles Conceptualization, Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: galter@mgh.harvard.edu (GA); lauffen@mit.edu (DAL); lwells@ccrc.uga.edu (LW)

  Affiliation Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA, United States of America

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