High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Stefano Castellana; Caterina Fusilli; Gianluigi Mazzoccoli; Tommaso Biagini; Daniele Capocefalo; Massimo Carella; Angelo Luigi Vescovi; Tommaso Mazza

doi:10.1371/journal.pcbi.1005628

Loading metrics

Open Access

Peer-reviewed

Research Article

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Stefano Castellana ,

Contributed equally to this work with: Stefano Castellana, Caterina Fusilli

Affiliation IRCCS Casa Sollievo della Sofferenza, Bioinformatics unit, San Giovanni Rotondo (FG), Italy

http://orcid.org/0000-0001-8688-9530

⨯
Caterina Fusilli ,

Contributed equally to this work with: Stefano Castellana, Caterina Fusilli

Affiliation IRCCS Casa Sollievo della Sofferenza, Bioinformatics unit, San Giovanni Rotondo (FG), Italy

http://orcid.org/0000-0001-7497-0657

⨯
Gianluigi Mazzoccoli,

Affiliation IRCCS Casa Sollievo della Sofferenza, Department of Medical Sciences, Division of Internal Medicine, San Giovanni Rotondo (FG), Italy
⨯
Tommaso Biagini,

Affiliation IRCCS Casa Sollievo della Sofferenza, Bioinformatics unit, San Giovanni Rotondo (FG), Italy
⨯
Daniele Capocefalo,

Affiliation IRCCS Casa Sollievo della Sofferenza, Bioinformatics unit, San Giovanni Rotondo (FG), Italy

http://orcid.org/0000-0001-7849-837X

⨯
Massimo Carella,

Affiliation IRCCS Casa Sollievo della Sofferenza, Medical Genetics unit, San Giovanni Rotondo (FG), Italy
⨯
Angelo Luigi Vescovi,

Affiliations IRCSS Casa Sollievo della Sofferenza, ISBReMIT- Institute for Stem Cell Biology, Regenerative Medicine and Innovative Therapies, San Giovanni Rotondo (FG), Italy, University of Milano Bicocca, Department of Biotechnology and Biosciences, Milan, Italy
⨯
Tommaso Mazza

* E-mail: t.mazza@css-mendel.it

Affiliation IRCCS Casa Sollievo della Sofferenza, Bioinformatics unit, San Giovanni Rotondo (FG), Italy

http://orcid.org/0000-0003-0434-8533

⨯

High-confidence assessment of functional impact of human mitochondrial non-synonymous genome variations by APOGEE

Stefano Castellana,
Caterina Fusilli,
Gianluigi Mazzoccoli,
Tommaso Biagini,
Daniele Capocefalo,
Massimo Carella,
Angelo Luigi Vescovi,
Tommaso Mazza

Published: June 22, 2017
https://doi.org/10.1371/journal.pcbi.1005628

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Pathogenesis
Is the Subject Area "Pathogenesis" applicable to this article?

Thanks for your feedback.
Decision trees
Is the Subject Area "Decision trees" applicable to this article?

Thanks for your feedback.
Genomics
Is the Subject Area "Genomics" applicable to this article?

Thanks for your feedback.
Algorithms
Is the Subject Area "Algorithms" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Deletion mutation
Is the Subject Area "Deletion mutation" applicable to this article?

Thanks for your feedback.
Mitochondrial DNA
Is the Subject Area "Mitochondrial DNA" applicable to this article?

Thanks for your feedback.