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Open Access
Peer-reviewed
Research Article
THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites
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Hsiao-Han Chang ,
* E-mail: hhchang@hsph.harvard.edu
Affiliation Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States
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Colin J. Worby,
Affiliation Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States
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Adoke Yeka,
Affiliations Makerere University School of Public Health, College of Health Sciences, Kampala, Uganda, Infectious Disease Research Collaboration, Kampala, Uganda
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Joaniter Nankabirwa,
Affiliations Infectious Disease Research Collaboration, Kampala, Uganda, Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda
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Moses R. Kamya,
Affiliations Infectious Disease Research Collaboration, Kampala, Uganda, Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda
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Sarah G. Staedke,
Affiliation London School of Hygiene and Tropical Medicine, London, United Kingdom
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Grant Dorsey,
Affiliation Department of Medicine, University of California, San Francisco, San Francisco, California, United States
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Maxwell Murphy,
Affiliation Department of Medicine, University of California, San Francisco, San Francisco, California, United States
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Daniel E. Neafsey,
Affiliation Genome Sequencing and Analysis Program, Broad Institute, Cambridge, Massachusetts, United States
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Anna E. Jeffreys,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Christina Hubbart,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Kirk A. Rockett,
Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Roberto Amato,
Affiliation Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Dominic P. Kwiatkowski,
Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Wellcome Trust Sanger Institute, Cambridge, United Kingdom
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Caroline O. Buckee ,
Contributed equally to this work with: Caroline O. Buckee, Bryan Greenhouse
Affiliation Center for Communicable Disease Dynamics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States
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Bryan Greenhouse
Contributed equally to this work with: Caroline O. Buckee, Bryan Greenhouse
Affiliation Department of Medicine, University of California, San Francisco, San Francisco, California, United States
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THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites
- Hsiao-Han Chang,
- Colin J. Worby,
- Adoke Yeka,
- Joaniter Nankabirwa,
- Moses R. Kamya,
- Sarah G. Staedke,
- Grant Dorsey,
- Maxwell Murphy,
- Daniel E. Neafsey,
- Anna E. Jeffreys
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- Published: January 26, 2017
- https://doi.org/10.1371/journal.pcbi.1005348