Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments

• Andrew K. Smith,

  Affiliation Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States of America

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• Brenden K. Petersen,

  Affiliation UCSF/UCB Joint Graduate Group in Bioengineering, University of California, Berkeley, Berkeley, CA, United States of America

  http://orcid.org/0000-0002-1841-3888

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• Glen E. P. Ropella,

  Affiliation Tempus Dictum, Inc., Milwaukie, OR, United States of America

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• Ryan C. Kennedy,

  Affiliation Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States of America

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• Neil Kaplowitz,

  Affiliation Division of Gastrointestinal and Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America

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• Murad Ookhtens,

  Affiliation Division of Gastrointestinal and Liver Diseases, Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America

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• C. Anthony Hunt

  * E-mail: a.hunt@ucsf.edu

  Affiliation Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States of America

  http://orcid.org/0000-0001-9372-6860

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