Stoichiometric Representation of Gene–Protein–Reaction Associations Leverages Constraint-Based Analysis from Reaction to Gene-Level Phenotype Prediction

• Daniel Machado ,

  * E-mail: dmachado@deb.uminho.pt

  Current address: Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

  Affiliation Centre of Biological Engineering, University of Minho, Braga, Portugal

  http://orcid.org/0000-0002-2063-5383

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• Markus J. Herrgård,

  Affiliation The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Horsølm, Denmark

  http://orcid.org/0000-0003-2377-9929

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• Isabel Rocha

  Affiliation Centre of Biological Engineering, University of Minho, Braga, Portugal

  http://orcid.org/0000-0001-9494-3410

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