HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates 13C Isotopomer Data

Carles Foguet; Silvia Marin; Vitaly A. Selivanov; Eric Fanchon; Wai-Nang Paul Lee; Joan J. Guinovart; Pedro de Atauri; Marta Cascante

doi:10.1371/journal.pcbi.1004899

Loading metrics

Open Access

Peer-reviewed

Research Article

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates ¹³C Isotopomer Data

Carles Foguet,

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute of Biomedicine of Universitat de Barcelona (IBUB) and Associated Unit to CSIC, Barcelona, Spain
⨯
Silvia Marin,

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute of Biomedicine of Universitat de Barcelona (IBUB) and Associated Unit to CSIC, Barcelona, Spain
⨯
Vitaly A. Selivanov,

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute of Biomedicine of Universitat de Barcelona (IBUB) and Associated Unit to CSIC, Barcelona, Spain
⨯
Eric Fanchon,

Affiliation UGA – CNRS, TIMC-IMAG UMR 5525, Grenoble, France
⨯
Wai-Nang Paul Lee,

Affiliation Department of Pediatrics, Los Angeles Biomedical Research Institute, Torrance, California, United States of America

http://orcid.org/0000-0002-0128-9112

⨯
Joan J. Guinovart,

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain
⨯
Pedro de Atauri ,

* E-mail: pde_atauri@ub.edu (PdA); martacascante@ub.edu (MC)

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute of Biomedicine of Universitat de Barcelona (IBUB) and Associated Unit to CSIC, Barcelona, Spain
⨯
Marta Cascante

* E-mail: pde_atauri@ub.edu (PdA); martacascante@ub.edu (MC)

Affiliations Department of Biochemistry and Molecular Biomedicine, Faculty of Biology, Universitat de Barcelona, Barcelona, Spain, Institute of Biomedicine of Universitat de Barcelona (IBUB) and Associated Unit to CSIC, Barcelona, Spain
⨯

HepatoDyn: A Dynamic Model of Hepatocyte Metabolism That Integrates ¹³C Isotopomer Data

Carles Foguet,
Silvia Marin,
Vitaly A. Selivanov,
Eric Fanchon,
Wai-Nang Paul Lee,
Joan J. Guinovart,
Pedro de Atauri,
Marta Cascante

Published: April 28, 2016
https://doi.org/10.1371/journal.pcbi.1004899

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Fructoses
Is the Subject Area "Fructoses" applicable to this article?

Thanks for your feedback.
Hepatocytes
Is the Subject Area "Hepatocytes" applicable to this article?

Thanks for your feedback.
Glucose
Is the Subject Area "Glucose" applicable to this article?

Thanks for your feedback.
Metabolic labeling
Is the Subject Area "Metabolic labeling" applicable to this article?

Thanks for your feedback.
Metabolites
Is the Subject Area "Metabolites" applicable to this article?

Thanks for your feedback.
Phosphates
Is the Subject Area "Phosphates" applicable to this article?

Thanks for your feedback.
Glycogens
Is the Subject Area "Glycogens" applicable to this article?

Thanks for your feedback.
Metabolic networks
Is the Subject Area "Metabolic networks" applicable to this article?

Thanks for your feedback.