Regulated CRISPR Modules Exploit a Dual Defense Strategy of Restriction and Abortive Infection in a Model of Prokaryote-Phage Coevolution

• M. Senthil Kumar ,

  * E-mail: smuthiah@umiacs.umd.edu (MSK); jplotkin@sas.upenn.edu (JBP); sridhar@umiacs.umd.edu (SH)

  Affiliations Graduate Program in Bioinformatics, University of Maryland, College Park, Maryland, United States of America, Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

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• Joshua B. Plotkin ,

  * E-mail: smuthiah@umiacs.umd.edu (MSK); jplotkin@sas.upenn.edu (JBP); sridhar@umiacs.umd.edu (SH)

  Affiliation Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Sridhar Hannenhalli

  * E-mail: smuthiah@umiacs.umd.edu (MSK); jplotkin@sas.upenn.edu (JBP); sridhar@umiacs.umd.edu (SH)

  Affiliation Center for Bioinformatics and Computational Biology, University of Maryland, College Park, Maryland, United States of America

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