Analyzing and Quantifying the Gain-of-Function Enhancement of IP₃ Receptor Gating by Familial Alzheimer’s Disease-Causing Mutants in Presenilins

• Don-On Daniel Mak,

  Affiliation Department of Physiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• King-Ho Cheung,

  Affiliation Department of Physiology, The University of Hong Kong, Pok Fu Lam, Hong Kong

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• Patrick Toglia,

  Affiliation Department of Physics, University of South Florida, Tampa, Florida, United States of America

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• J. Kevin Foskett,

  Affiliations Department of Physiology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America, Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

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• Ghanim Ullah

  * E-mail: gullah@usf.edu

  Affiliation Department of Physics, University of South Florida, Tampa, Florida, United States of America

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