Systematic Prediction of Scaffold Proteins Reveals New Design Principles in Scaffold-Mediated Signal Transduction

Open Access

Peer-reviewed

Research Article

Jianfei Hu,

Affiliation Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Johnathan Neiswinger,

Affiliation Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Jin Zhang,

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, Solomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Heng Zhu,

Affiliations Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, Center for High-Throughput Biology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Jiang Qian

* E-mail: jiang.qian@jhmi.edu

Affiliations Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
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Phosphorylation
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Protein interaction networks
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Protein kinase signaling cascade
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Protein domains
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Protein interactions
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Protein kinases
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Signal transduction
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Signaling networks
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