Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening

• Claire Colas ,

  Contributed equally to this work with: Claire Colas, Christof Grewer, Nicholas James Otte

  Affiliation Department of Pharmacology and Systems Therapeutics, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Christof Grewer ,

  Contributed equally to this work with: Claire Colas, Christof Grewer, Nicholas James Otte

  Affiliation Department of Chemistry, Binghamton University, Binghamton, New York, United States of America

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• Nicholas James Otte ,

  Contributed equally to this work with: Claire Colas, Christof Grewer, Nicholas James Otte

  Affiliations Origins of Cancer Laboratory Centenary Program, Camperdown, Australia, Sydney Medical School, University of Sydney, Sydney, Australia

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• Armanda Gameiro,

  Affiliation Department of Chemistry, Binghamton University, Binghamton, New York, United States of America

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• Thomas Albers,

  Affiliation Department of Chemistry, Binghamton University, Binghamton, New York, United States of America

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• Kurnvir Singh,

  Affiliation Department of Chemistry, Binghamton University, Binghamton, New York, United States of America

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• Helen Shere,

  Affiliation Department of Pharmacology and Systems Therapeutics, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Massimiliano Bonomi,

  Affiliation Department of Chemistry, University of Cambridge, Cambridge, United Kingdom

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• Jeff Holst ,

  * E-mail: j.holst@centenary.org.au (JH); avner.schlessinger@mssm.edu (AS)

  Affiliations Origins of Cancer Laboratory Centenary Program, Camperdown, Australia, Sydney Medical School, University of Sydney, Sydney, Australia

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• Avner Schlessinger

  * E-mail: j.holst@centenary.org.au (JH); avner.schlessinger@mssm.edu (AS)

  Affiliation Department of Pharmacology and Systems Therapeutics, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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