Examination of the Effects of Heterogeneous Organization of RyR Clusters, Myofibrils and Mitochondria on Ca²⁺ Release Patterns in Cardiomyocytes

• Vijay Rajagopal ,

  Contributed equally to this work with: Vijay Rajagopal, Gregory Bass

  * E-mail: vijay.rajagopal@unimelb.edu.au

  Affiliations Department of Mechanical Engineering, University of Melbourne, Melbourne, Australia, Auckland Bioengineering Institute, University of Auckland, Auckland, New Zealand, Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, Melbourne, Australia

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• Gregory Bass ,

  Contributed equally to this work with: Vijay Rajagopal, Gregory Bass

  Affiliation Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, Melbourne, Australia

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• Cameron G. Walker,

  Affiliation Department of Engineering Science, University of Auckland, Auckland, New Zealand

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• David J. Crossman,

  Affiliation Department of Physiology, University of Auckland, Auckland, New Zealand

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• Amorita Petzer,

  Affiliation School of Biological Sciences, University of Auckland, Auckland. New Zealand

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• Anthony Hickey,

  Affiliation School of Biological Sciences, University of Auckland, Auckland. New Zealand

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• Ivo Siekmann,

  Affiliation Department of Mechanical Engineering, University of Melbourne, Melbourne, Australia

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• Masahiko Hoshijima,

  Affiliations Department of Medicine, University of California San Diego, San Diego, United States of America, National Center for Microscopy and Imaging Research, University of California San Diego, San Diego, United States of America

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• Mark H. Ellisman,

  Affiliation National Center for Microscopy and Imaging Research, University of California San Diego, San Diego, United States of America

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• Edmund J. Crampin,

  Affiliations Systems Biology Laboratory, Melbourne School of Engineering, University of Melbourne, Melbourne, Australia, School of Mathematics and Statistics, Faculty of Science, University of Melbourne, Melbourne, Australia, School of Medicine, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia, ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, University of Melbourne, Melbourne, Australia

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• Christian Soeller

  Affiliations Department of Physiology, University of Auckland, Auckland, New Zealand, Biomedical Physics, University of Exeter, Exeter, United Kingdom

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