Quantitative Analysis of the Association Angle between T-cell Receptor Vα/Vβ Domains Reveals Important Features for Epitope Recognition

Open Access

Peer-reviewed

Research Article

Thomas Hoffmann,

Affiliation Department of Biosciences and Center for Integrated Protein Science Munich,Technische Universität München, Freising-Weihenstephan, Germany
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Angela M. Krackhardt,

Affiliations Medizinische Klinik III, Innere Medizin mit Schwerpunkt Hämatologie und Onkologie, Technische Universität München, Munich, Germany, Clinical Cooperation Group, Antigen specific T cell therapy, Helmholtz Zentrum München (GmbH), German Center for Environmental Health, Munich, Germany, German Cancer Consortium (DKTK), Munich, Germany
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Iris Antes

* E-mail: antes@tum.de

Affiliation Department of Biosciences and Center for Integrated Protein Science Munich,Technische Universität München, Freising-Weihenstephan, Germany
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T cell receptors
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Major histocompatibility complex
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Crystal structure
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Hydrogen bonding
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T cells
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TCR signaling cascade
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Geometry
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Pattern recognition receptors
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