Improved Statistical Methods Enable Greater Sensitivity in Rhythm Detection for Genome-Wide Data

Alan L. Hutchison; Mark Maienschein-Cline; Andrew H. Chiang; S. M. Ali Tabei; Herman Gudjonson; Neil Bahroos; Ravi Allada; Aaron R. Dinner

doi:10.1371/journal.pcbi.1004094

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Research Article

Improved Statistical Methods Enable Greater Sensitivity in Rhythm Detection for Genome-Wide Data

Alan L. Hutchison ,

¶‡ These authors contributed equally to the manuscript.

Affiliations Medical Scientist Training Program, University of Chicago, Chicago, Illinois, United States of America, Graduate Program in the Biophysical Sciences, University of Chicago, Chicago, Illinois, United States of America, James Franck Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
Mark Maienschein-Cline ,

¶‡ These authors contributed equally to the manuscript.

Affiliation Center for Research Informatics, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Andrew H. Chiang ,

¶‡ These authors contributed equally to the manuscript.

Affiliation James Franck Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
S. M. Ali Tabei,

Present address: Physics Department University of Northern Iowa Cedar Falls, Iowa 50614

Affiliation James Franck Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
Herman Gudjonson,

Affiliations Graduate Program in the Biophysical Sciences, University of Chicago, Chicago, Illinois, United States of America, James Franck Institute, University of Chicago, Chicago, Illinois, United States of America
⨯
Neil Bahroos,

Affiliation Center for Research Informatics, University of Illinois at Chicago, Chicago, Illinois, United States of America
⨯
Ravi Allada,

Affiliation Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Aaron R. Dinner

* E-mail: dinner@uchicago.edu

Affiliations Graduate Program in the Biophysical Sciences, University of Chicago, Chicago, Illinois, United States of America, James Franck Institute, University of Chicago, Chicago, Illinois, United States of America, Department of Chemistry, University of Chicago, Chicago, Illinois, United States of America
⨯

Improved Statistical Methods Enable Greater Sensitivity in Rhythm Detection for Genome-Wide Data

Alan L. Hutchison,
Mark Maienschein-Cline,
Andrew H. Chiang,
S. M. Ali Tabei,
Herman Gudjonson,
Neil Bahroos,
Ravi Allada,
Aaron R. Dinner

Published: March 20, 2015
https://doi.org/10.1371/journal.pcbi.1004094

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Gene expression
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