Mapping the Pareto Optimal Design Space for a Functionally Deimmunized Biotherapeutic Candidate

Open Access

Peer-reviewed

Research Article

Regina S. Salvat,

Affiliation Thayer School of Engineering, Dartmouth, Hanover, New Hampshire, United States of America
⨯
Andrew S. Parker,

Current address: Zettics, Concord, Massachusetts, United States of America

Affiliation Department of Computer Science, Dartmouth, Hanover, New Hampshire, United States of America
⨯
Yoonjoo Choi,

Affiliation Department of Computer Science, Dartmouth, Hanover, New Hampshire, United States of America
⨯
Chris Bailey-Kellogg ,

* E-mail: cbk@cs.dartmouth.edu (CBK); karl.e.griswold@dartmouth.edu (KEG)

Affiliation Department of Computer Science, Dartmouth, Hanover, New Hampshire, United States of America
⨯
Karl E. Griswold

* E-mail: cbk@cs.dartmouth.edu (CBK); karl.e.griswold@dartmouth.edu (KEG)

Affiliations Thayer School of Engineering, Dartmouth, Hanover, New Hampshire, United States of America, Program in Molecular and Cellular Biology, Dartmouth, Hanover, New Hampshire, United States of America
⨯

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Major histocompatibility complex
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Antigens
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T cells
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Immune system proteins
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Deletion mutation
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Forecasting
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Substitution mutation
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Synthetic biotherapeutics
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