Immuno-epidemiological Modeling of HIV-1 Predicts High Heritability of the Set-Point Virus Load, while Selection for CTL Escape Dominates Virulence Evolution

Open Access

Peer-reviewed

Research Article

Christiaan H. van Dorp ,

* E-mail: C.H.vanDorp@uu.nl

Affiliations Theoretical Biology and Bioinformatics, Universiteit Utrecht, Utrecht, The Netherlands, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
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Michiel van Boven,

Affiliation National Institute for Public Health and the Environment, Bilthoven, The Netherlands
⨯
Rob J. de Boer

Affiliation Theoretical Biology and Bioinformatics, Universiteit Utrecht, Utrecht, The Netherlands
⨯

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HIV-1
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Deletion mutation
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Microbial mutation
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Immune response
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Viral evolution
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Evolutionary immunology
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Evolutionary adaptation
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Heredity
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