Modeling Dynamics of Cell-to-Cell Variability in TRAIL-Induced Apoptosis Explains Fractional Killing and Predicts Reversible Resistance

Open Access

Peer-reviewed

Research Article

François Bertaux,

Affiliation INRIA Paris-Rocquencourt, Le Chesnay, France
⨯
Szymon Stoma,

Current address: ScopeM, ETH Zürich, Zürich, Switzerland

Affiliation INRIA Paris-Rocquencourt, Le Chesnay, France
⨯
Dirk Drasdo,

Affiliations INRIA Paris-Rocquencourt, Le Chesnay, France, Laboratoire Jacques-Louis Lions (LJLL), University of Paris 6 (UPMC) - CNRS (UMR7598), Paris, France
⨯
Gregory Batt

* E-mail: gregory.batt@inria.fr

Affiliation INRIA Paris-Rocquencourt, Le Chesnay, France
⨯

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Apoptosis
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Signal transduction
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Protein synthesis
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Messenger RNA
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Gene expression
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Cell cycle and cell division
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HeLa cells
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Transcription factors
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