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Open Access
Peer-reviewed
Research Article
The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing
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Jaclyn K. Mann ,
Contributed equally to this work with: Jaclyn K. Mann, John P. Barton, Andrew L. Ferguson
Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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John P. Barton ,
Contributed equally to this work with: Jaclyn K. Mann, John P. Barton, Andrew L. Ferguson
Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America
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Andrew L. Ferguson ,
Contributed equally to this work with: Jaclyn K. Mann, John P. Barton, Andrew L. Ferguson
Affiliation Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America
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Saleha Omarjee,
Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa
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Bruce D. Walker,
Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America
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Arup Chakraborty ,
* E-mail: arupc@mit.edu (AC); ndungu@ukzn.ac.za (TN)
Affiliations Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America, Departments of Chemistry and Physics, Massachusetts Institute of Technology, Boston, Massachusetts, United States of America
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Thumbi Ndung'u
* E-mail: arupc@mit.edu (AC); ndungu@ukzn.ac.za (TN)
Affiliations HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, KwaZulu-Natal Research Institute for Tuberculosis and HIV (K-RITH), Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Boston, Massachusetts, United States of America, Max Planck Institute for Infection Biology, Berlin, Germany
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The Fitness Landscape of HIV-1 Gag: Advanced Modeling Approaches and Validation of Model Predictions by In Vitro Testing
- Jaclyn K. Mann,
- John P. Barton,
- Andrew L. Ferguson,
- Saleha Omarjee,
- Bruce D. Walker,
- Arup Chakraborty,
- Thumbi Ndung'u
- Published: August 7, 2014
- https://doi.org/10.1371/journal.pcbi.1003776