Allele-Specific Network Reveals Combinatorial Interaction That Transcends Small Effects in Psoriasis GWAS

Open Access

Peer-reviewed

Research Article

Sharlee Climer ,

* E-mail: climer@wustl.edu (SC); weixiong.zhang@wustl.edu (WZ)

Affiliation Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America
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Alan R. Templeton,

Affiliations Department of Biology, Washington University, St. Louis, Missouri, United States of America, Department of Genetics, Washington University, St. Louis, Missouri, United States of America, Institute of Evolution, and Department of Evolutionary and Environmental Biology, University of Haifa, Haifa, Israel
⨯
Weixiong Zhang

* E-mail: climer@wustl.edu (SC); weixiong.zhang@wustl.edu (WZ)

Affiliations Department of Computer Science and Engineering, Washington University, St. Louis, Missouri, United States of America, Department of Genetics, Washington University, St. Louis, Missouri, United States of America, Institute for Systems Biology, Jianghan University, Wuhan, Hubei, China
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Single nucleotide polymorphisms
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Psoriasis
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Genome-wide association studies
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Network analysis
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Genetics of disease
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Permutation
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Variant genotypes
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Medical risk factors
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