Mechanistic, Mathematical Model to Predict the Dynamics of Tissue Genesis in Bone Defects via Mechanical Feedback and Mediation of Biochemical Factors

• Shannon R. Moore,

  Affiliation Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Gerald M. Saidel ,

  * E-mail: gms3@case.edu (GMS); m.knothetate@unsw.edu.au (MLKT)

  Affiliation Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Ulf Knothe,

  Affiliation Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio, United States of America

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• Melissa L. Knothe Tate

  * E-mail: gms3@case.edu (GMS); m.knothetate@unsw.edu.au (MLKT)

  Affiliations Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Mechanical & Aerospace Engineering, Case Western Reserve University, Cleveland, Ohio, United States of America, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia

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