Microenvironmental Variables Must Influence Intrinsic Phenotypic Parameters of Cancer Stem Cells to Affect Tumourigenicity

• Jacob G. Scott ,

  * E-mail: jacob.g.scott@gmail.com (JGS); david@CancerEvo.org (DB)

  Affiliations Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, Wolfson Centre for Mathematical Biology, Mathematical Institute, University of Oxford, Oxford, United Kingdom

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• Anita B. Hjelmeland,

  Affiliation Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Prakash Chinnaiyan,

  Affiliation Department of Radiation Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• Alexander R. A. Anderson,

  Affiliation Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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• David Basanta

  * E-mail: jacob.g.scott@gmail.com (JGS); david@CancerEvo.org (DB)

  Affiliation Integrated Mathematical Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America

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