The Role of Flexibility and Conformational Selection in the Binding Promiscuity of PDZ Domains

Open Access

Peer-reviewed

Research Article

Márton Münz,

Affiliations Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, United Kingdom, Department of Statistics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom
⨯
Jotun Hein,

Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom
⨯
Philip C. Biggin

* E-mail: philip.biggin@bioch.ox.ac.uk

Affiliations Structural Bioinformatics and Computational Biochemistry, University of Oxford, Oxford, United Kingdom, Oxford Centre for Integrative Systems Biology, Department of Biochemistry, Oxford, United Kingdom
⨯

Reader Comments (0)

Protein domains
Is the Subject Area "Protein domains" applicable to this article?

Thanks for your feedback.
Crystal structure
Is the Subject Area "Crystal structure" applicable to this article?

Thanks for your feedback.
Antigen-presenting cells
Is the Subject Area "Antigen-presenting cells" applicable to this article?

Thanks for your feedback.
Molecular dynamics
Is the Subject Area "Molecular dynamics" applicable to this article?

Thanks for your feedback.
Point mutation
Is the Subject Area "Point mutation" applicable to this article?

Thanks for your feedback.
Protein structure
Is the Subject Area "Protein structure" applicable to this article?

Thanks for your feedback.
Protein structure comparison
Is the Subject Area "Protein structure comparison" applicable to this article?

Thanks for your feedback.
Simulation and modeling
Is the Subject Area "Simulation and modeling" applicable to this article?

Thanks for your feedback.