Does Mutational Robustness Inhibit Extinction by Lethal Mutagenesis in Viral Populations?

Open Access

Peer-reviewed

Research Article

Eamon B. O'Dea,

Affiliation Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America
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Thomas E. Keller,

Affiliation Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America
⨯
Claus O. Wilke

* E-mail: cwilke@mail.utexas.edu

Affiliations Section of Integrative Biology, The University of Texas at Austin, Austin, Texas, United States of America, Center for Computational Biology and Bioinformatics and Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, Texas, United States of America
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Mutagenesis
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Extinct genomes
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Microbial mutation
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Biochemical simulations
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RNA viruses
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Viral evolution
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Bacterial lethality
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Deletion mutation
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