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Open Access

Peer-reviewed

Research Article

Mutation Bias Favors Protein Folding Stability in the Evolution of Small Populations

Raul Mendez ,

Contributed equally to this work with: Raul Mendez, Miriam Fritsche

Affiliation Centro de Biología Molecular “Severo Ochoa”, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain
⨯
Miriam Fritsche ,

Contributed equally to this work with: Raul Mendez, Miriam Fritsche

Current address: Institut für Theoretische Physik, Ruprecht-Karls-Universität Heidelberg, Heidelberg, Germany

Affiliation Institut für Festkörperphysik, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Markus Porto ,

* E-mail: porto@thp.uni-koeln.de; ubastolla@cbm.uam.es

Current address: Institut für Theoretische Physik, Universität zu Köln, Köln, Germany

Affiliation Institut für Festkörperphysik, Technische Universität Darmstadt, Darmstadt, Germany
⨯
Ugo Bastolla

* E-mail: porto@thp.uni-koeln.de; ubastolla@cbm.uam.es

Affiliation Centro de Biología Molecular “Severo Ochoa”, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Madrid, Spain
⨯

Mutation Bias Favors Protein Folding Stability in the Evolution of Small Populations

Raul Mendez,
Miriam Fritsche,
Markus Porto,
Ugo Bastolla

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Published: May 6, 2010
https://doi.org/10.1371/journal.pcbi.1000767

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Population size
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Protein folding
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Effective population size
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Molecular evolution
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Genomics
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Entropy
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Biochemical simulations
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Microbial mutation
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