A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

Qing Xie; Qi Liu; Fengbiao Mao; Wanshi Cai; Honghu Wu; Mingcong You; Zhen Wang; Bingyu Chen; Zhong Sheng Sun; Jinyu Wu

doi:10.1371/journal.pcbi.1003853

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Open Access

Peer-reviewed

Research Article

A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

Qing Xie ,

Contributed equally to this work with: Qing Xie, Qi Liu

Affiliation Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China
⨯
Qi Liu ,

Contributed equally to this work with: Qing Xie, Qi Liu

Affiliation Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China
⨯
Fengbiao Mao,

Affiliation Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China
⨯
Wanshi Cai,

Affiliation Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China
⨯
Honghu Wu,

Affiliation Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China
⨯
Mingcong You,

Affiliation Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China
⨯
Zhen Wang,

Affiliation Institute of Molecular Medicine, Department of blood transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China
⨯
Bingyu Chen,

Affiliation Institute of Molecular Medicine, Department of blood transfusion, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China
⨯
Zhong Sheng Sun ,

* E-mail: zsunusa@yahoo.com (ZSS); iamwujy@gmail.com (JW)

Affiliations Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China, Beijing Institutes of Life Science, Chinese Academy of Sciences, Beijing, China
⨯
Jinyu Wu

* E-mail: zsunusa@yahoo.com (ZSS); iamwujy@gmail.com (JW)

Affiliation Institute of Genomic Medicine, Wenzhou Medical University, Wenzhou, China
⨯

A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

Qing Xie,
Qi Liu,
Fengbiao Mao,
Wanshi Cai,
Honghu Wu,
Mingcong You,
Zhen Wang,
Bingyu Chen,
Zhong Sheng Sun,
Jinyu Wu

Published: September 25, 2014
https://doi.org/10.1371/journal.pcbi.1003853

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Is there a software package available?

Posted by reilly_brian_m on 09 Dec 2015 at 21:13 GMT

I did not see an associated software package in the manuscript. IS this Bycom model available or going to be available in the future as a software package?

No competing interests declared.

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Methylation
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Cytosine
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DNA methylation
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Genomics
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Heterozygosity
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Silkworms
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High throughput sequencing
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Simulation and modeling
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A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

A Bayesian Framework to Identify Methylcytosines from High-Throughput Bisulfite Sequencing Data

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Is there a software package available?

Posted by reilly_brian_m on 09 Dec 2015 at 21:13 GMT