About the Authors

Ping Xu

Contributed equally to this work with: Ping Xu, Zile Luo, Xi Chen

Roles Data curation, Formal analysis, Visualization, Writing – review & editing

Affiliations BGI Research, Chongqing, China, BGI College & Henan Institute of Medical and Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, China

Zile Luo

Contributed equally to this work with: Ping Xu, Zile Luo, Xi Chen

Roles Data curation, Formal analysis, Methodology, Validation, Visualization, Writing – review & editing

Affiliations BGI Research, Chongqing, China, College of Life Sciences, University of Chinese Academy of Sciences, Beijing, China

Xi Chen

Contributed equally to this work with: Ping Xu, Zile Luo, Xi Chen

Roles Funding acquisition, Investigation, Validation

Affiliations BGI Research, Chongqing, China, State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Shenzhen, China

Zhongyang Yuan

Roles Formal analysis

Affiliation BGI Research, Chongqing, China

Le Cheng

Roles Supervision

Affiliation BGI Research, Kunming, China

Yi Yang

Roles Supervision

Affiliation BGI Research, Kunming, China

Hongcheng Lin

Roles Funding acquisition, Supervision, Writing – review & editing, Conceptualization

lhcheng@mail.sysu.edu.cn (HL); 1153776174@qq.com (QZ); pengf.qin@outlook.com (PQ)

Affiliations Department of General Surgery (Department of Coloproctology), The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

Qiong Zhang

Roles Supervision, Writing – review & editing, Conceptualization

lhcheng@mail.sysu.edu.cn (HL); 1153776174@qq.com (QZ); pengf.qin@outlook.com (PQ)

Affiliation Department of Obstetrics and Reproductive Medicine, Affiliated Hospital of Yunnan University, Kunming, Yunnan, China

Pengfei Qin

Roles Formal analysis, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing, Conceptualization

lhcheng@mail.sysu.edu.cn (HL); 1153776174@qq.com (QZ); pengf.qin@outlook.com (PQ)

Affiliations BGI Research, Chongqing, China, State Key Laboratory of Genome and Multi-omics Technologies, BGI Research, Shenzhen, China, Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou, Henan, China

Competing Interests

The authors have declared that no competing interests exist.