About the Authors

Jianda Yue

Contributed equally to this work with: Jianda Yue, Tingting Li

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – review & editing

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Tingting Li

Contributed equally to this work with: Jianda Yue, Tingting Li

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Jian Ouyang

Roles Investigation, Validation

Affiliations Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, China, National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, China

Jiawei Xu

Roles Data curation, Investigation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Hua Tan

Roles Investigation, Validation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Zihui Chen

Roles Investigation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Changsheng Han

Roles Validation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Huanyu Li

Roles Validation

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Songping Liang

Roles Resources, Supervision

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Zhonghua Liu

Roles Conceptualization, Funding acquisition, Resources, Supervision, Conceptualization, Funding acquisition, Resources, Supervision

liuzh@hunnu.edu.cn (ZL); zhonghua-liu-ms@hunau.edu.cn (ZL); wangyin@hunnu.edu.cn (YW)

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Zhonghua Liu

Roles Conceptualization, Funding acquisition, Resources, Supervision, Conceptualization, Funding acquisition, Resources, Supervision

liuzh@hunnu.edu.cn (ZL); zhonghua-liu-ms@hunau.edu.cn (ZL); wangyin@hunnu.edu.cn (YW)

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China, Key Laboratory of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha, China, National Research Center of Engineering Technology for Utilization of Functional Ingredients from Botanicals, Hunan Agricultural University, Changsha, China

Ying Wang

Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

liuzh@hunnu.edu.cn (ZL); zhonghua-liu-ms@hunau.edu.cn (ZL); wangyin@hunnu.edu.cn (YW)

Affiliations The National and Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, China, Peptide and small molecule drug R&D plateform, Furong Laboratory, Hunan Normal University, Changsha, Hunan, China, Institute of Interdisciplinary Studies, Hunan Normal University, Changsha, Hunan, China

Competing Interests

The authors have declared that no competing interests exist.