About the Authors

Chrysovalantis Voutouri

Roles Conceptualization, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

cvouto01@ucy.ac.cy (CV); tstylian@ucy.ac.cy (TS); lmunn@mgh.harvard.edu (LLM); rjain@mgh.harvard.edu (RKJ)

Affiliation Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus

Lance L. Munn

Roles Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

cvouto01@ucy.ac.cy (CV); tstylian@ucy.ac.cy (TS); lmunn@mgh.harvard.edu (LLM); rjain@mgh.harvard.edu (RKJ)

Affiliation Edwin L Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Triantafyllos Stylianopoulos

Roles Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

cvouto01@ucy.ac.cy (CV); tstylian@ucy.ac.cy (TS); lmunn@mgh.harvard.edu (LLM); rjain@mgh.harvard.edu (RKJ)

Affiliation Cancer Biophysics Laboratory, Department of Mechanical and Manufacturing Engineering, University of Cyprus, Nicosia, Cyprus

Rakesh K. Jain

Roles Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

cvouto01@ucy.ac.cy (CV); tstylian@ucy.ac.cy (TS); lmunn@mgh.harvard.edu (LLM); rjain@mgh.harvard.edu (RKJ)

Affiliation Edwin L Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

I have read the journal's policy and the authors of this manuscript have the following competing interests: LLM owns equity in Bayer AG and is a consultant for SimBiosys. RKJ received consultant fees from DynamiCure, SPARC, SynDevRx; owns equity in Accurius, Enlight, Ophthotech, SynDevRx; and served on the Boards of Trustees of Tekla Healthcare Investors, Tekla Life Sciences Investors, Tekla Healthcare Opportunities Fund, Tekla World Healthcare Fund; and received a grant from Sanofi. Neither any reagent nor any funding from these organizations was used in this study. Other co-authors have no conflict of interests to declare.