About the Authors

Daniel J.B. Clarke

Roles Conceptualization, Formal analysis, Methodology, Software, Visualization, Writing – original draft

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

John Erol Evangelista

Roles Formal analysis, Software, Visualization

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Zhuorui Xie

Roles Software, Visualization

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Giacomo B. Marino

Roles Software, Visualization

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Anna I. Byrd

Roles Data curation

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Mano R. Maurya

Roles Software, Visualization, Writing – original draft

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Sumana Srinivasan

Roles Software, Visualization, Writing – original draft

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Keyang Yu

Roles Software, Visualization, Writing – original draft

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Varduhi Petrosyan

Roles Software, Visualization, Writing – original draft

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Matthew E. Roth

Roles Project administration, Supervision

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Miroslav Milinkov

Roles Software

Affiliation Persida Inc., Brooklyn, New York, United States of America

Charles Hadley King

Roles Software, Writing – original draft

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Jeet Kiran Vora

Roles Project administration, Software, Supervision, Visualization

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Jonathon Keeney

Roles Software, Writing – original draft

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Christopher Nemarich

Roles Project administration

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

William Khan

Roles Software

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Alexander Lachmann

Roles Software

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Nasheath Ahmed

Roles Software

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Alexandra Agris

Roles Software

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Juncheng Pan

Roles Software

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Srinivasan Ramachandran

Roles Software

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Eoin Fahy

Roles Software

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Emmanuel Esquivel

Roles Software

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Aleksandar Mihajlovic

Roles Project administration, Supervision

Affiliation Persida Inc., Brooklyn, New York, United States of America

Bosko Jevtic

Roles Software

Affiliation Persida Inc., Brooklyn, New York, United States of America

Vuk Milinovic

Roles Software

Affiliation Persida Inc., Brooklyn, New York, United States of America

Sean Kim

Roles Software

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Patrick McNeely

Roles Software

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Tianyi Wang

Roles Software

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Eric Wenger

Roles Project administration

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Miguel A. Brown

Roles Software

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Alexander Sickler

Roles Software

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Yuankun Zhu

Roles Software

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Sherry L. Jenkins

Roles Project administration, Supervision

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Philip D. Blood

Roles Supervision

Affiliation Pittsburgh Supercomputing Center, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

Deanne M. Taylor

Roles Funding acquisition, Supervision

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Adam C. Resnick

Roles Funding acquisition, Supervision

Affiliations Department of Biomedical and Health Informatics; Department of Pediatrics, The Children’s Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America, Center for Data Driven Discovery in Biomedicine, The Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania, United States of America

Raja Mazumder

Roles Funding acquisition, Supervision

Affiliation Department of Biochemistry and Molecular Medicine, The George Washington School of Medicine and Health Sciences, Washington, DC, United States of America

Aleksandar Milosavljevic

Roles Funding acquisition, Supervision

Affiliation Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America

Shankar Subramaniam

Roles Funding acquisition, Supervision

Affiliation Department of Bioengineering, University of California San Diego, La Jolla, California, United States of America

Avi Ma’ayan

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Software, Supervision, Writing – original draft, Writing – review & editing

avi.maayan@mssm.edu

Affiliation Department of Pharmacological Sciences, Windreich Department of Artificial Intelligence and Human Health, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.