Structural prediction of chimeric immunogen candidates to elicit targeted antibodies against betacoronaviruses

Jamel Simpson; Peter M. Kasson

doi:10.1371/journal.pcbi.1012812

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Open Access

Peer-reviewed

Research Article

Structural prediction of chimeric immunogen candidates to elicit targeted antibodies against betacoronaviruses

Jamel Simpson,

Roles Formal analysis, Investigation, Software, Writing – review & editing

Affiliation Program in Biophysics and Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America
⨯
Peter M. Kasson

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: kassonlab@gmail.com

Affiliations Program in Biophysics and Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America, Departments of Chemistry and Biochemistry and Biomedical Engineering, Georgia Institute of Technology, Atlanta, GeorgiaUnited States of America, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

https://orcid.org/0000-0002-3111-8103

⨯

Structural prediction of chimeric immunogen candidates to elicit targeted antibodies against betacoronaviruses

Jamel Simpson,
Peter M. Kasson

Published: February 5, 2025
https://doi.org/10.1371/journal.pcbi.1012812

About the Authors

Jamel Simpson

Roles Formal analysis, Investigation, Software, Writing – review & editing

Affiliation Program in Biophysics and Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America

Peter M. Kasson

Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

* E-mail: kassonlab@gmail.com

Affiliations Program in Biophysics and Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, United States of America, Departments of Chemistry and Biochemistry and Biomedical Engineering, Georgia Institute of Technology, Atlanta, GeorgiaUnited States of America, Department of Cell and Molecular Biology, Uppsala University, Uppsala, Sweden

https://orcid.org/0000-0002-3111-8103

Competing Interests

The authors have declared that no competing interests exist.

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SARS CoV 2
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Molecular dynamics
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Biochemical simulations
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Antigens
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Protein structure prediction
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Antibodies
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Coronaviruses
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Virus testing
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