Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders

Romani Osbourne; Kelly M. Thayer

doi:10.1371/journal.pcbi.1012382

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Open Access

Peer-reviewed

Research Article

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders

Romani Osbourne ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft

* E-mail: rosbourne@wesleyan.edu

Affiliations Department of Molecular Biology & Biochemistry, Wesleyan University, Middletown, Connecticut, United States of America, College of Integrative Sciences, Wesleyan University, Middletown, Connecticut, United States of America

https://orcid.org/0009-0000-3947-7509

⨯
Kelly M. Thayer

Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing

Affiliation College of Integrative Sciences, Wesleyan University, Middletown, Connecticut, United States of America
⨯

Structural and mechanistic diversity in p53-mediated regulation of organismal longevity across taxonomical orders

Romani Osbourne,
Kelly M. Thayer

Published: May 2, 2025
https://doi.org/10.1371/journal.pcbi.1012382

About the Authors

Romani Osbourne

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft

* E-mail: rosbourne@wesleyan.edu

Affiliations Department of Molecular Biology & Biochemistry, Wesleyan University, Middletown, Connecticut, United States of America, College of Integrative Sciences, Wesleyan University, Middletown, Connecticut, United States of America

https://orcid.org/0009-0000-3947-7509

Kelly M. Thayer

Roles Conceptualization, Funding acquisition, Resources, Supervision, Validation, Writing – review & editing

Affiliation College of Integrative Sciences, Wesleyan University, Middletown, Connecticut, United States of America

Competing Interests

The authors have declared that no competing interests exist.

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Cancers and neoplasms
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Transactivation
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Phylogenetics
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Sequence alignment
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Animal phylogenetics
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Multiple alignment calculation
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Primates
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Taxonomy
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