About the Authors

Belén Casas

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden, Department of Biomedical Engineering, Linköping University, Linköping, Sweden

Liisa Vilén

Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Writing – review & editing

Affiliation Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Sophie Bauer

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation TissUse GmbH, Berlin, Germany

Kajsa P. Kanebratt

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Charlotte Wennberg Huldt

Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Lisa Magnusson

Roles Investigation, Methodology, Writing – review & editing

Affiliation Bioscience, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Uwe Marx

Roles Methodology, Resources, Writing – review & editing

Affiliation TissUse GmbH, Berlin, Germany

Tommy B. Andersson

Roles Methodology, Project administration, Resources, Writing – review & editing

Affiliation Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

Peter Gennemark

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

‡ These authors are shared senior authors on this work.

Affiliations Drug Metabolism and Pharmacokinetics, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden, Department of Biomedical Engineering, Linköping University, Linköping, Sweden

Gunnar Cedersund

Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

gunnar.cedersund@liu.se

‡ These authors are shared senior authors on this work.

Affiliations Department of Biomedical Engineering, Linköping University, Linköping, Sweden, Center for Medical Image Science and Visualization (CMIV), Linköping University, Linköping, Sweden

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: L.V., K.PK., C.WH., L.M., T.BA., P.G. are employees of AstraZeneca and hold stock/stock options. AstraZeneca also provided support in the form of salary for B.C.. U.M is shareholder and CSO of TissUse GmbH, which commercializes MPS platforms.