A computational grid-to-place-cell transformation model indicates a synaptic driver of place cell impairment in early-stage Alzheimer’s Disease

Open Access

Peer-reviewed

Research Article

About the Authors

Natalie Ness

Roles Conceptualization, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Centre for Neurotechnology and Department of Bioengineering, Imperial College London, London, United Kingdom

Simon R. Schultz

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

Affiliation Centre for Neurotechnology and Department of Bioengineering, Imperial College London, London, United Kingdom

The authors have declared that no competing interests exist.

Synapses
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Pyramidal cells
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Cognitive impairment
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Interneurons
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Alzheimer's disease
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Hippocampus
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Mouse models
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Synaptic plasticity
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