Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions

Yao Jiang; Hui-Fang Liu; Rong Liu

doi:10.1371/journal.pcbi.1008951

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Open Access

Peer-reviewed

Research Article

Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions

Yao Jiang ,

Contributed equally to this work with: Yao Jiang, Hui-Fang Liu

Roles Formal analysis, Investigation, Software, Validation, Visualization

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China
⨯
Hui-Fang Liu ,

Contributed equally to this work with: Yao Jiang, Hui-Fang Liu

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China
⨯
Rong Liu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: liurong116@mail.hzau.edu.cn

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China

https://orcid.org/0000-0001-9603-398X

⨯

Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions

Yao Jiang,
Hui-Fang Liu,
Rong Liu

Published: April 19, 2021
https://doi.org/10.1371/journal.pcbi.1008951

About the Authors

Yao Jiang

Contributed equally to this work with: Yao Jiang, Hui-Fang Liu

Roles Formal analysis, Investigation, Software, Validation, Visualization

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China

Hui-Fang Liu

Contributed equally to this work with: Yao Jiang, Hui-Fang Liu

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China

Rong Liu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: liurong116@mail.hzau.edu.cn

Affiliation Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan, P. R. China

https://orcid.org/0000-0001-9603-398X

Competing Interests

The authors have declared that no competing interests exist.

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Free energy
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Nucleotides
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Algorithms
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Protein interactions
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Forecasting
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Mutation databases
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Hydrogen bonding
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Nucleic acids
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