The evolutionary origin of the universal distribution of mutation fitness effect

Ayuna Barlukova; Igor M. Rouzine

doi:10.1371/journal.pcbi.1008822

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Open Access

Peer-reviewed

Research Article

The evolutionary origin of the universal distribution of mutation fitness effect

Ayuna Barlukova,

Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft

Affiliation Sorbonne Université, Institute de Biologie Paris-Seine, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France
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Igor M. Rouzine

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: igor.rouzine@sorbonne-universite.fr, ivan4995@gmail.com

Affiliation Sorbonne Université, Institute de Biologie Paris-Seine, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France

https://orcid.org/0000-0002-0744-6705

⨯

The evolutionary origin of the universal distribution of mutation fitness effect

Ayuna Barlukova,
Igor M. Rouzine

Published: March 8, 2021
https://doi.org/10.1371/journal.pcbi.1008822

About the Authors

Ayuna Barlukova

Roles Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft

Affiliation Sorbonne Université, Institute de Biologie Paris-Seine, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France

Igor M. Rouzine

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: igor.rouzine@sorbonne-universite.fr, ivan4995@gmail.com

Affiliation Sorbonne Université, Institute de Biologie Paris-Seine, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France

https://orcid.org/0000-0002-0744-6705

Competing Interests

The authors have declared that no competing interests exist.

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Genomics
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Traveling waves
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Deletion mutation
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Epistasis
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Viral evolution
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Evolutionary adaptation
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Genome evolution
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Natural selection
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