Pre-existing resistance in the latent reservoir can compromise VRC01 therapy during chronic HIV-1 infection

Ananya Saha; Narendra M. Dixit

doi:10.1371/journal.pcbi.1008434

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Open Access

Peer-reviewed

Research Article

Pre-existing resistance in the latent reservoir can compromise VRC01 therapy during chronic HIV-1 infection

Ananya Saha,

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Department of Chemical Engineering, Indian Institute of Science, Bengaluru, India
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Narendra M. Dixit

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: narendra@iisc.ac.in

Affiliations Department of Chemical Engineering, Indian Institute of Science, Bengaluru, India, Centre for Biosystems Science and Engineering, Indian Institute of Science, Bengaluru, India

https://orcid.org/0000-0002-2145-9828

⨯

Pre-existing resistance in the latent reservoir can compromise VRC01 therapy during chronic HIV-1 infection

Ananya Saha,
Narendra M. Dixit

Published: November 30, 2020
https://doi.org/10.1371/journal.pcbi.1008434

About the Authors

Ananya Saha

Roles Data curation, Formal analysis, Methodology, Writing – original draft

Affiliation Department of Chemical Engineering, Indian Institute of Science, Bengaluru, India

Narendra M. Dixit

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

* E-mail: narendra@iisc.ac.in

Affiliations Department of Chemical Engineering, Indian Institute of Science, Bengaluru, India, Centre for Biosystems Science and Engineering, Indian Institute of Science, Bengaluru, India

https://orcid.org/0000-0002-2145-9828

Competing Interests

The authors declare that no competing interests exist.

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Antiretroviral therapy
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Genomics
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HIV-1
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Virions
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Viral replication
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Viral evolution
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Viremia
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Clinical trials
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