Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures

Elan Shatoff; Ralf Bundschuh

doi:10.1371/journal.pcbi.1007852

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Open Access

Peer-reviewed

Research Article

Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures

Elan Shatoff,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Physics, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America

http://orcid.org/0000-0003-4632-2286

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Ralf Bundschuh

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: bundschuh@mps.ohio-state.edu

Affiliations Department of Physics, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America, Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

http://orcid.org/0000-0002-6699-8614

⨯

Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures

Elan Shatoff,
Ralf Bundschuh

Published: May 7, 2020
https://doi.org/10.1371/journal.pcbi.1007852

About the Authors

Elan Shatoff

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliations Department of Physics, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America

http://orcid.org/0000-0003-4632-2286

Ralf Bundschuh

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: bundschuh@mps.ohio-state.edu

Affiliations Department of Physics, The Ohio State University, Columbus, Ohio, United States of America, Center for RNA Biology, The Ohio State University, Columbus, Ohio, United States of America, Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

http://orcid.org/0000-0002-6699-8614

Competing Interests

The authors have declared that no competing interests exist.

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Single nucleotide polymorphisms
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RNA-binding proteins
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RNA structure
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Nucleotide sequencing
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Protein structure
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Nucleotides
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Protein structure determination
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Protein structure prediction
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