scPADGRN: A preconditioned ADMM approach for reconstructing dynamic gene regulatory network using single-cell RNA sequencing data

Xiao Zheng; Yuan Huang; Xiufen Zou

doi:10.1371/journal.pcbi.1007471

Loading metrics

Open Access

Peer-reviewed

Research Article

scPADGRN: A preconditioned ADMM approach for reconstructing dynamic gene regulatory network using single-cell RNA sequencing data

Xiao Zheng,

Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft

Affiliation School of Mathematics and Statistics, Wuhan University, Wuhan, Hubei, China
⨯
Yuan Huang,

Roles Formal analysis, Methodology, Project administration, Validation, Writing – review & editing

Affiliation Department of Biostatistics, Yale University, New Haven, Connecticut, United States of America
⨯
Xiufen Zou

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: xfzou@whu.edu.cn

Affiliation School of Mathematics and Statistics, Wuhan University, Wuhan, Hubei, China

http://orcid.org/0000-0001-5294-0764

⨯

scPADGRN: A preconditioned ADMM approach for reconstructing dynamic gene regulatory network using single-cell RNA sequencing data

Xiao Zheng,
Yuan Huang,
Xiufen Zou

Published: July 27, 2020
https://doi.org/10.1371/journal.pcbi.1007471
See the preprint

About the Authors

Xiao Zheng

Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – original draft

Affiliation School of Mathematics and Statistics, Wuhan University, Wuhan, Hubei, China

Yuan Huang

Roles Formal analysis, Methodology, Project administration, Validation, Writing – review & editing

Affiliation Department of Biostatistics, Yale University, New Haven, Connecticut, United States of America

Xiufen Zou

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: xfzou@whu.edu.cn

Affiliation School of Mathematics and Statistics, Wuhan University, Wuhan, Hubei, China

http://orcid.org/0000-0001-5294-0764

Competing Interests

The authors have declared that no competing interests exist.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cell differentiation
Is the Subject Area "Cell differentiation" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Regulator genes
Is the Subject Area "Regulator genes" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Genetic networks
Is the Subject Area "Genetic networks" applicable to this article?

Thanks for your feedback.
Stem cells
Is the Subject Area "Stem cells" applicable to this article?

Thanks for your feedback.
Network analysis
Is the Subject Area "Network analysis" applicable to this article?

Thanks for your feedback.
Gene regulatory networks
Is the Subject Area "Gene regulatory networks" applicable to this article?

Thanks for your feedback.