About the Authors

Wei Zheng

Roles Investigation, Methodology, Writing – original draft

Affiliations Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America, College of Mathematical Sciences and LPMC, Nankai University, Tianjin, PR China

Qiqige Wuyun

Roles Investigation, Software, Validation

Affiliations College of Mathematical Sciences and LPMC, Nankai University, Tianjin, PR China, Computer Science and Engineering Department, Michigan State University, East Lansing, MI, United States of America

Yang Li

Roles Methodology, Software

Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America

S. M. Mortuza

Roles Software, Validation

Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America

Chengxin Zhang

Roles Software, Validation

Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America

Robin Pearce

Roles Writing – review & editing

Affiliation Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America

Jishou Ruan

Roles Funding acquisition, Supervision

Affiliations College of Mathematical Sciences and LPMC, Nankai University, Tianjin, PR China, State Key Laboratory of Medicinal Chemical Biology, Nankai University, Tianjin, PR China

Yang Zhang

Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft

zhng@umich.edu

Affiliations Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, United States of America, Department of Biological Chemistry, University of Michigan, Ann Arbor, MI, United States of America

Competing Interests

The authors have declared that no competing interests exist.