About the Authors

Shu Wang

Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Affiliations Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Harvard Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America

Jia-Ren Lin

Roles Data curation, Formal analysis, Investigation, Supervision

Affiliation Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Eduardo D. Sontag

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – review & editing

Affiliations Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America, Departments of Electrical and Computer Engineering and of Bioengineering, Northeastern University, Boston, Massachusetts, United States of America

Peter K. Sorger

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

peter_sorger@hms.harvard.edu

Affiliation Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

I have read the journal’s policy and the authors of this manuscript have the following competing interests: PKS is a member of the SAB or Board of Directors of Merrimack Pharmaceutical, Glencoe Software, Applied Biomath, and RareCyte and has received research funding from Novartis and Merck. PKS declares that none of these relationships are directly or indirectly related to the content of this manuscript.