Machine learning-based microarray analyses indicate low-expression genes might collectively influence PAH disease

Song Cui; Qiang Wu; James West; Jiangping Bai

doi:10.1371/journal.pcbi.1007264

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Open Access

Peer-reviewed

Research Article

Machine learning-based microarray analyses indicate low-expression genes might collectively influence PAH disease

Song Cui,

Roles Writing – original draft, Writing – review & editing

Affiliations College of Agronomy, Gansu Agricultural University, Lanzhou, Gansu, China, School of Agriculture, Middle Tennessee State University, Murfreesboro, Tennessee, United States of America
⨯
Qiang Wu,

Roles Formal analysis, Methodology

Affiliation Department of Mathematics, Middle Tennessee State University, Murfreesboro, Tennessee, United States of America

http://orcid.org/0000-0002-4698-6966

⨯
James West,

Roles Conceptualization, Data curation, Methodology, Resources

Affiliation Department of Medicine, Pulmonary Vascular Research Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Jiangping Bai

Roles Supervision

* E-mail: baijp@gsau.edu.cn

Affiliation College of Agronomy, Gansu Agricultural University, Lanzhou, Gansu, China

http://orcid.org/0000-0002-2532-1631

⨯

Machine learning-based microarray analyses indicate low-expression genes might collectively influence PAH disease

Song Cui,
Qiang Wu,
James West,
Jiangping Bai

Published: August 12, 2019
https://doi.org/10.1371/journal.pcbi.1007264

About the Authors

Song Cui

Roles Writing – original draft, Writing – review & editing

Affiliations College of Agronomy, Gansu Agricultural University, Lanzhou, Gansu, China, School of Agriculture, Middle Tennessee State University, Murfreesboro, Tennessee, United States of America

Qiang Wu

Roles Formal analysis, Methodology

Affiliation Department of Mathematics, Middle Tennessee State University, Murfreesboro, Tennessee, United States of America

http://orcid.org/0000-0002-4698-6966

James West

Roles Conceptualization, Data curation, Methodology, Resources

Affiliation Department of Medicine, Pulmonary Vascular Research Institute, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Jiangping Bai

Roles Supervision

* E-mail: baijp@gsau.edu.cn

Affiliation College of Agronomy, Gansu Agricultural University, Lanzhou, Gansu, China

http://orcid.org/0000-0002-2532-1631

Competing Interests

The authors have declared that no competing interests exist.

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Machine learning algorithms
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Algorithms
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Gene expression
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Microarrays
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Artificial neural networks
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Support vector machines
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Hierarchical clustering
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Machine learning
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